Tet2 and relevant potential intervention in cancer
<p>5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxycytosine (5caC) are products of TET enzyme activity, which initiates at 5-methylcytosine (5mC) in DNA. 5hmC has been found to be globally depleted in cancer, while <em>TET2</em> is highly mutated. The first obje...
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| Format: | Thesis |
| Language: | English |
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2014
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