HIV-1 attachment: another look.
HIV-1 attachment to host cells is generally considered to take place via high-affinity binding between CD4 and gp120. However, the binding of virion-associated gp120 to cellular CD4 is often weak, and most cell types that are permissive for HIV-1 infection express little CD4. Thus, other interaction...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
1999
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