RNA therapy for polyglutamine neurodegenerative diseases.
Polyglutamine neurodegenerative diseases result from the expansion of a trinucleotide CAG repeat, encoding a polyglutamine tract in the disease-causing protein. The process by which each polyglutamine protein exerts its toxicity is complex, involving a variety of mechanisms including transcriptional...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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