Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection.
Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 are important targets for the host immune response. The genes encoding these proteins exhibit a high degree of variability that gives rise to differing phenotypic traits, including alterations in receptor-binding affinity and immune recognitio...
Main Authors: | , , , , , , , , |
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格式: | Journal article |
语言: | English |
出版: |
2005
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