Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection.

Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 are important targets for the host immune response. The genes encoding these proteins exhibit a high degree of variability that gives rise to differing phenotypic traits, including alterations in receptor-binding affinity and immune recognitio...

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Bibliographic Details
Main Authors: Brown, R, Juttla, V, Tarr, A, Finnis, R, Irving, W, Hemsley, S, Flower, DR, Borrow, P, Ball, J
Format: Journal article
Language:English
Published: 2005