Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.

HLA-B*27 exerts protective effects in hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections. While the immunological and virological features of HLA-B*27-mediated protection are not fully understood, there is growing evidence that the presentation of specific immunodominant HLA-B...

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Bibliographic Details
Main Authors: Schmidt, J, Iversen, A, Tenzer, S, Gostick, E, Price, D, Lohmann, V, Distler, U, Bowness, P, Schild, H, Blum, H, Klenerman, P, Neumann-Haefelin, C, Thimme, R
Format: Journal article
Language:English
Published: Public Library of Science 2012