TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy

<p>Background: Tumour-specific radiosensitising treatments may enhance the efficacy of radiotherapy without exacerbating side effects. In this study we determined the radiation response following depletion or inhibition of TOPK, a MAPKK family Ser/Thr protein kinase that is upregulat...

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Bibliographic Details
Main Authors: Pirovano, G, Ashton, T, Herbert, K, Bryant, R, Verrill, C, Cerundolo, L, Buffa, F, Prevo, R, Harrap, I, Ryan, A, Macaulay, V, McKenna, W, Higgins, G
Format: Journal article
Published: Cancer Research UK 2017