Role of HR23B, HDAC6 and Myd88 and their interplay in response to HDAC inhibitor treatment
Abnormal epigenetic control is a common early event in tumour progression, and aberrant acetylation in particular has been implicated in tumourigenesis. Histone deacetylases (HDACs) are enzymes that regulate acetylation of chromatin and a variety of other non-histone substrates. Significantly, HDAC...
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| Format: | Thesis |
| Language: | English |
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2014
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