Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.

We undertook a two-stage genome-wide association study (GWAS) of Alzheimer's disease (AD) involving over 16,000 individuals, the most powerful AD GWAS to date. In stage 1 (3,941 cases and 7,848 controls), we replicated the established association with the apolipoprotein E (APOE) locus (most sig...

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Bibliographic Details
Main Authors:	Harold, D, Abraham, R, Hollingworth, P, Sims, R, Gerrish, A, Hamshere, M, Pahwa, J, Moskvina, V, Dowzell, K, Williams, A, Jones, N, Thomas, C, Stretton, A, Morgan, A, Lovestone, S, Powell, J, Proitsi, P, Lupton, M, Brayne, C, Rubinsztein, D, Gill, M, Lawlor, B, Lynch, A, Morgan, K, Brown, K
Format:	Journal article
Language:	English
Published:	2009

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.

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