Insights into the role of the von Hippel-Lindau gene product. A key player in hypoxic regulation.
Many adaptive responses to hypoxia involve changes in gene transcription mediated by the hypoxia-inducible factor 1 complex. Central to this is oxygen-dependent proteolysis of the alpha subunit, which has recently been shown to require the von Hippel-Lindau tumour-suppressor protein. This observatio...
| Váldodahkkit: | , , |
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| Materiálatiipa: | Journal article |
| Giella: | English |
| Almmustuhtton: |
2001
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