Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model.
<p><strong>BACKGROUND</strong></p> <p>Apolipoprotein E (ApoE), a cholesterol carrier associated with atherosclerosis, is a major risk factor for Alzheimer&apos;s disease (AD). The low-density lipoprotein receptor (LDLR) regulates ApoE levels in the periphery and...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
PLoS
2011
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