Hydrometallation-asymmetric conjugate addition: application to complex molecule synthesis.
Copper catalysis allows alkyl zirconium species, generated in situ from alkenes, to undergo conjugate addition reactions. A hydrometallation-catalytic asymmetric 1,4-addition was used to synthesize either enantiomer of a natural product in one step from commercially available materials. Hydrometalla...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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