The role of mechanics in the growth and homeostasis of the intestinal crypt
We present a mechanical model of tissue homeostasis that is specialised to the intestinal crypt. Growth and deformation of the crypt, idealised as a line of cells on a substrate, are modelled using morphoelastic rod theory. Alternating between Lagrangian and Eulerian mechanical descriptions enables...
Main Authors: | Almet, AA, Byrne, H, Maini, P, Moulton, D |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Springer
2020
|
Similar Items
-
Modelling perspectives on the intestinal crypt, a canonical system for growth, mechanics and remodelling
by: Almet, A, et al.
Published: (2020) -
Biomechanics of intestinal crypt morphogenesis
by: Almet, A
Published: (2019) -
Re-evaluating the Role of Deep Crypt Secretory Cells in Intestinal Homeostasis
by: Huw McCarthy, et al.
Published: (2023-01-01) -
Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts.
by: Murray, P, et al.
Published: (2010) -
Modelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal Crypts
by: Murray, P, et al.
Published: (2010)