High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart.

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) stimulates calcium release from acidic stores such as lysosomes and is a highly potent calcium-mobilising second messenger. NAADP plays an important role in calcium signalling in the heart under basal conditions and following β-adrenergic stress....

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Aston, D, Capel, R, Ford, K, Christian, H, Mirams, G, Rog-Zielinska, E, Kohl, P, Galione, A, Burton, R, Terrar, D
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Nature Publishing Group 2017