Simultaneous voltage and calcium mapping of genetically purified human induced pluripotent stem cell-derived cardiac myocyte monolayers.

RATIONALE: Human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) offer a powerful in vitro tool to investigate disease mechanisms and to perform patient-specific drug screening. To date, electrophysiological analysis of iPSC-CMs has been limited to single-cell recordings or low-resol...

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Main Authors: Lee, P, Klos, M, Bollensdorff, C, Hou, L, Ewart, P, Kamp, T, Zhang, J, Bizy, A, Guerrero-Serna, G, Kohl, P, Jalife, J, Herron, T
Formato: Journal article
Idioma:English
Publicado: 2012