Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor.

Collagen-induced arthritis can be transferred into severe combined immunodeficiency (SCID) mice by spleen cells from diseased DBA/1 mice. The development of arthritis in SCID animals can be prevented by infection ex vivo of DBA/1 spleen cells with retroviruses expressing the monomeric soluble human...

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Bibliographic Details
Main Authors: Chernajovsky, Y, Adams, G, Podhajcer, O, Mueller, G, Robbins, P, Feldmann, M
Format: Journal article
Language:English
Published: 1995