Arginine methylation in the E2F1 pathway
<p>The E2F1 pathway plays an important role in coordinating early cell cycle progression. Deregulation of the E2F1 pathway, which may be brought about by somatic mutations in genes such as INK4A, RB1 and CDK4, is found in a majority of cancers. The transcription factor E2F1 is able to activate...
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Format: | Thesis |
Language: | English |
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2013
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