Targeted delivery of small interfering RNA to angiogenic endothelial cells with liposome-polycation-DNA particles.

Angiogenesis is an attractive target for cancer therapy, due to its central position in tumor growth and development. Vascular Endothelial Growth Factor (VEGF) and its receptors (VEGFRs) play a key role in the angiogenic process. A promising strategy for targeting VEGF-mediated angiogenesis is RNA i...

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Bibliographic Details
Main Authors: Vader, P, Crielaard, B, van Dommelen, S, van der Meel, R, Storm, G, Schiffelers, R
Format: Journal article
Language:English
Published: 2012