Making the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugs.

Mechanistic within-host models integrating blood anti-malarial drug concentrations with the parasite-time profile provide a valuable decision tool for determining dosing regimens for anti-malarial treatments, as well as a formative component of population-level drug resistance models. We reviewed pu...

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Bibliographic Details
Main Authors: Simpson, J, Zaloumis, S, DeLivera, A, Price, R, McCaw, J
Format: Journal article
Language:English
Published: 2014