A total synthesis of salinosporamide A
Salinosporamide A is a β‐lactone proteasome inhibitor currently in clinical trials for the treatment of multiple‐myeloma. Herein we report a short synthesis of this small, highly functionalized, biologically important natural product that uses an oxidative radical cyclization as a key step and allo...
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Format: | Journal article |
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Wiley
2018
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