Detection and selective dissociation of intact ribosomes in a mass spectrometer.

Intact Escherichia coli ribosomes have been projected into the gas phase of a mass spectrometer by means of nanoflow electrospray techniques. Species with mass/charge ratios in excess of 20,000 were detected at the level of individual ions by using time-of-flight analysis. Once in the gas phase the...

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Bibliographic Details
Main Authors: Rostom, A, Fucini, P, Benjamin, DR, Juenemann, R, Nierhaus, K, Hartl, F, Dobson, C, Robinson, C
Format: Journal article
Language:English
Published: 2000