Active genes are tri-methylated at K4 of histone H3.

Lysine methylation of histones in vivo occurs in three states: mono-, di- and tri-methyl. Histone H3 has been found to be di-methylated at lysine 4 (K4) in active euchromatic regions but not in silent heterochromatic sites. Here we show that the Saccharomyces cerevisiae Set1 protein can catalyse di-...

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Bibliographic Details
Main Authors: Santos-Rosa, H, Schneider, R, Bannister, A, Sherriff, J, Bernstein, B, Emre, N, Schreiber, S, Mellor, J, Kouzarides, T
Format: Journal article
Language:English
Published: 2002