Active genes are tri-methylated at K4 of histone H3.
Lysine methylation of histones in vivo occurs in three states: mono-, di- and tri-methyl. Histone H3 has been found to be di-methylated at lysine 4 (K4) in active euchromatic regions but not in silent heterochromatic sites. Here we show that the Saccharomyces cerevisiae Set1 protein can catalyse di-...
Main Authors: | Santos-Rosa, H, Schneider, R, Bannister, A, Sherriff, J, Bernstein, B, Emre, N, Schreiber, S, Mellor, J, Kouzarides, T |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2002
|
Similar Items
-
Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin.
by: Santos-Rosa, H, et al.
Published: (2003) -
WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development.
by: Wysocka, J, et al.
Published: (2005) -
Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription.
by: Morillon, A, et al.
Published: (2005) -
Investigations on small molecule inhibitors targeting the histone H3K4 tri-methyllysine binding PHD-finger of JmjC histone demethylases
by: Bhushan, B, et al.
Published: (2018) -
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation.
by: Edmunds, J, et al.
Published: (2008)