Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase.

Mass spectrometric screening reveals that an unmodified natural heptapeptide--human beta-casomorphin-7, an internal sequence of human beta-casein that possesses opioid-like activity--reacts with porcine pancreatic elastase to form an unusually stable acyl-enzyme complex at low pH. X-ray crystallogra...

Full description

Bibliographic Details
Main Authors: Wilmouth, R, Clifton, I, Robinson, C, Roach, P, Aplin, RT, Westwood, N, Hajdu, J, Schofield, C
Format: Journal article
Language:English
Published: 1997