Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase.
Mass spectrometric screening reveals that an unmodified natural heptapeptide--human beta-casomorphin-7, an internal sequence of human beta-casein that possesses opioid-like activity--reacts with porcine pancreatic elastase to form an unusually stable acyl-enzyme complex at low pH. X-ray crystallogra...
Main Authors: | Wilmouth, R, Clifton, I, Robinson, C, Roach, P, Aplin, RT, Westwood, N, Hajdu, J, Schofield, C |
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Format: | Journal article |
Language: | English |
Published: |
1997
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