Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria.

BACKGROUND: Acute kidney injury (AKI) complicating severe Plasmodium falciparum malaria occurs in up to 40% of adult patients. The case fatality rate reaches 75% in the absence of renal replacement therapy (RRT). The precise pathophysiology of AKI in falciparum malaria remains unclear. Histopatholog...

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Bibliographic Details
Main Authors: Plewes, K, Royakkers, A, Hanson, J, Hasan, M, Alam, S, Ghose, A, Maude, R, Stassen, P, Charunwatthana, P, Lee, S, Turner, G, Dondorp, A, Schultz, M
Format: Journal article
Language:English
Published: BioMed Central 2014