Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria.

Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria.

BACKGROUND: Acute kidney injury (AKI) complicating severe Plasmodium falciparum malaria occurs in up to 40% of adult patients. The case fatality rate reaches 75% in the absence of renal replacement therapy (RRT). The precise pathophysiology of AKI in falciparum malaria remains unclear. Histopatholog...

Full description

Bibliographic Details
Main Authors:	Plewes, K, Royakkers, A, Hanson, J, Hasan, M, Alam, S, Ghose, A, Maude, R, Stassen, P, Charunwatthana, P, Lee, S, Turner, G, Dondorp, A, Schultz, M
Format:	Journal article
Language:	English
Published:	BioMed Central 2014

Similar Items

Laboratory prediction of the requirement for renal replacement in acute falciparum malaria.
by: Hanson, J, et al.
Published: (2011)

Pathophysiology, clinical presentation, and treatment of coma and acute kidney injury complicating falciparum malaria
by: Plewes, K, et al.
Published: (2018)

Defining surrogate endpoints for clinical trials in severe Falciparum malaria.
by: Jeeyapant, A, et al.
Published: (2017)

Laboratory prediction of the requirement for renal replacement in acute falciparum malaria
by: Yunus Emran, et al.
Published: (2011-08-01)

Sequestration and red cell deformability as determinants of hyperlactatemia in falciparum malaria
by: Ishioka, H, et al.
Published: (2015)

The predictive capacity of biomarkers for clinical pulmonary oedema in patients with severe falciparum malaria is low: a prospective observational study
by: Ishioka, H, et al.
Published: (2024)

Magnetic resonance imaging of the brain in adults with severe falciparum malaria.
by: Maude, R, et al.
Published: (2014)

IN VIVO EVIDENCE THAT MICROCIRCULATORY OBSTRUCTION IS A CENTRAL PATHOLOGICAL PROCESS IN SEVERE FALCIPARUM MALARIA
by: Maude, R, et al.
Published: (2010)

Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study.
by: Plewes, K, et al.
Published: (2017)

The clinical implications of thrombocytopenia in adults with severe falciparum malaria: a retrospective analysis
by: Hanson, J, et al.
Published: (2015)

Relative contributions of macrovascular and microvascular dysfunction to disease severity in falciparum malaria.
by: Hanson, J, et al.
Published: (2012)

Reduced cardiac index reserve and hypovolemia in severe falciparum malaria
by: Kingston, H, et al.
Published: (2019)

The spectrum of retinopathy in adults with Plasmodium falciparum malaria.
by: Maude, R, et al.
Published: (2009)

Disease severity and effective parasite multiplication rate in falciparum aalaria.
by: Kingston, H, et al.
Published: (2017)

Parasite burden and severity of malaria in Tanzanian children.
by: Woodrow, C, et al.
Published: (2014)

Intravascular haemolysis, oxidative stress and acute kidney injury in severe falciparum malaria
by: Plewes, K
Published: (2015)

Direct in vivo assessment of microcirculatory dysfunction in severe falciparum malaria.
by: Dondorp, A, et al.
Published: (2008)

Randomized controlled trial of levamisole hydrochloride as adjunctive therapy in severe falciparum malaria with high parasitemia.
by: Maude, R, et al.
Published: (2014)

Does reduced oxygen delivery cause lactic acidosis in falciparum malaria? An observational study
by: Kingston, H, et al.
Published: (2019)

Fluid resuscitation of adults with severe falciparum malaria: effects on Acid-base status, renal function, and extravascular lung water.
by: Hanson, J, et al.
Published: (2013)

Fluid resuscitation of adults with severe falciparum malaria: Effects on acid-base status, renal function, and extravascular lung water
by: Hanson, J, et al.
Published: (2013)

Amino acid derangements in adults with severe falciparum malaria
by: Leopold, S, et al.
Published: (2019)

Associations Between Restrictive Fluid Management and Renal Function and Tissue Perfusion in Adults With Severe Falciparum Malaria: A Prospective Observational Study
by: Ishioka, H, et al.
Published: (2019)

Artesunate dosing in severe falciparum malaria.
by: Dondorp, A, et al.
Published: (2012)

Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study
by: Katherine Plewes, et al.
Published: (2017-04-01)

Artemisinin resistance in falciparum malaria
by: Dondorp, A
Published: (2012)

Identifying the components of acidosis in patients with severe plasmodium falciparum malaria Using metabolomics
by: Leopold, S, et al.
Published: (2018)

Does artesunate prolong the electrocardiograph QT interval in patients with severe malaria?
by: Maude, R, et al.
Published: (2009)

Reversibility of retinal microvascular changes in severe falciparum malaria.
by: Maude, R, et al.
Published: (2014)

Levamisole inhibits sequestration of infected red blood cells in patients with falciparum malaria.
by: Dondorp, A, et al.
Published: (2007)

Estimating malaria disease burden in the Asia-Pacific
by: Maude, RJ, et al.
Published: (2019)

The mechanisms of parasite clearance after antimalarial treatment of Plasmodium falciparum malaria.
by: Chotivanich, K, et al.
Published: (2000)

Acidosis and acute kidney injury in severe malaria
by: Sriboonvorakul, N, et al.
Published: (2018)

Malaria: what’s new in the management of malaria?
by: Plewes, K, et al.
Published: (2019)

Rapid clinical assessment to facilitate the triage of adults with falciparum malaria, a retrospective analysis.
by: Hanson, J, et al.
Published: (2014)

Artemisinin resistance and stage dependency of parasite clearance in Falciparum malaria
by: Intharabut, B, et al.
Published: (2019)

Pharmacokinetic properties of intramuscular versus oral syrup paracetamol in Plasmodium falciparum malaria
by: Wattanakul, T, et al.
Published: (2016)

Pharmacokinetic properties of intramuscular versus oral syrup paracetamol in Plasmodium falciparum malaria.
by: Wattanakul, T, et al.
Published: (2016)

Oscillations in cerebral haemodynamics in patients with falciparum malaria.
by: Kolyva, C, et al.
Published: (2013)

Does reduced oxygen delivery cause lactic acidosis in falciparum malaria? An observational study
by: Hugh W. Kingston, et al.
Published: (2019-03-01)