TETRAZOLES OF MANNO-PYRANOSES AND RHAMNO-PYRANOSES - INHIBITION OF GLYCOSIDASES BY TETRAZOLES AND OTHER MANNOSE MIMICS

The synthesis of tetrazoles derived from D-mannopyranose and D-rhamnopyranose from L-gulonolactone is described. These and other materials are assessed as inhibitors of human liver glycosidases and delineate some structural features required for α- and β-mannosidase and α-fucosidase inhibition. © 19...

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Bibliographic Details
Main Authors: Brandstetter, T, Davis, B, Hyett, D, Smith, C, Hackett, L, Winchester, B, Fleet, G
Format: Journal article
Language:English
Published: 1995