Innate immune responses to human malaria: heterogeneous cytokine responses to blood-stage Plasmodium falciparum correlate with parasitological and clinical outcomes.

Taking advantage of a sporozoite challenge model established to evaluate the efficacy of new malaria vaccine candidates, we have explored the kinetics of systemic cytokine responses during the prepatent period of Plasmodium falciparum infection in 18 unvaccinated, previously malaria-naive subjects,...

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Bibliographic Details
Main Authors: Walther, M, Woodruff, J, Edele, F, Jeffries, D, Tongren, J, King, E, Andrews, L, Bejon, P, Gilbert, S, De Souza, J, Sinden, R, Hill, A, Riley, E
Format: Journal article
Language:English
Published: 2006