High hyperdiploidy among adolescents and adults with acute lymphoblastic leukaemia (ALL): cytogenetic features, clinical characteristics and outcome.

High hyperdiploidy (HeH, 51-65 chromosomes) is an established genetic subtype of acute lymphoblastic leukaemia (ALL). The clinical and cytogenetic features as well as outcome of HeH among adolescents and adults have not been thoroughly investigated. Among 1232 B-cell precursor ALL patients (15-65 ye...

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Bibliographic Details
Main Authors: Chilton, L, Buck, G, Harrison, C, Ketterling, R, Rowe, J, Tallman, MS, Goldstone, A, Fielding, A, Moorman, A
Format: Journal article
Language:English
Published: Nature Publishing Group 2014