Spatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum.

BACKGROUND: Plasmodium falciparum has repeatedly evolved resistance to first-line anti-malarial drugs, thwarting efforts to control and eliminate the disease and in some period of time this contributed largely to an increase in mortality. Here a mathematical model was developed to map the spatiotemp...

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Bibliographic Details
Main Authors: Flegg, J, Patil, A, Venkatesan, M, Roper, C, Naidoo, I, Hay, S, Sibley, C, Guerin, P
Format: Journal article
Language:English
Published: BioMed Central 2013