Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.

Agonists of the allosteric benzodiazepine site of GABAA receptors bind at the interface of the alpha and gamma subunits. Here, we tested the in vivo contribution of the gamma2 subunit to the actions of zolpidem, an alpha1 subunit selective benzodiazepine agonist, by generating mice with a phenylalan...

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Bibliographic Details
Main Authors:	Cope, D, Wulff, P, Oberto, A, Aller, M, Capogna, M, Ferraguti, F, Halbsguth, C, Hoeger, H, Jolin, H, Jones, A, McKenzie, A, Ogris, W, Poeltl, A, Sinkkonen, S, Vekovischeva, O, Korpi, E, Sieghart, W, Sigel, E, Somogyi, P, Wisden, W
Format:	Journal article
Language:	English
Published:	2004

Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.

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