Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease.

Recent findings suggest that production of pro-inflammatory cytokines, such as tumour necrosis factor-alpha (TNF-alpha), is increased in the brains of people with Alzheimer's disease (AD). We used direct sequencing methods on a section of the enhancer/promoter region and on a smaller fragment l...

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Bibliographic Details
Main Authors: Culpan, D, MacGowan, S, Ford, J, Nicoll, J, Griffin, W, Dewar, D, Cairns, N, Hughes, A, Kehoe, P, Wilcock, G
Format: Journal article
Language:English
Published: 2003