Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank
<br><strong>Aims/hypothesis: </strong>Previous evidence linking red meat consumption with diabetes risk mainly came from western countries, with little evidence from China, where patterns of meat consumption are different. Moreover, global evidence remains inconclusive about the as...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Springer
2020
|
| _version_ | 1797052679406485504 |
|---|---|
| author | Du, H Guo, Y Bennett, DA Bragg, F Bian, Z Chadni, M Yu, C Chen, Y Tan, Y Millwood, IY Gan, W Yang, L Yao, P Luo, G Li, J Qin, Y Lv, J Lin, X Key, T Chen, J Clarke, R Li, L Chen, Z China Kadoorie Biobank collaborative group |
| author_facet | Du, H Guo, Y Bennett, DA Bragg, F Bian, Z Chadni, M Yu, C Chen, Y Tan, Y Millwood, IY Gan, W Yang, L Yao, P Luo, G Li, J Qin, Y Lv, J Lin, X Key, T Chen, J Clarke, R Li, L Chen, Z China Kadoorie Biobank collaborative group |
| author_sort | Du, H |
| collection | OXFORD |
| description | <br><strong>Aims/hypothesis: </strong>Previous evidence linking red meat consumption with diabetes risk mainly came from western countries, with little evidence from China, where patterns of meat consumption are different. Moreover, global evidence remains inconclusive about the associations of poultry and fish consumption with diabetes. Therefore we investigated the associations of red meat, poultry and fish intake with incidence of diabetes in a Chinese population.</br>
<br><strong>Methods: </strong>The prospective China Kadoorie Biobank recruited ~512,000 adults (59% women, mean age 51 years) from ten rural and urban areas across China in 2004–2008. At the baseline survey, a validated interviewer-administered laptop-based questionnaire was used to collect information on the consumption frequency of major food groups including red meat, poultry, fish, fresh fruit and several others. During ~9 years of follow-up, 14,931 incidences of new-onset diabetes were recorded among 461,036 participants who had no prior diabetes, cardiovascular diseases or cancer at baseline. Cox regression analyses were performed to calculate adjusted HRs for incident diabetes associated with red meat, poultry and fish intake.</br>
<br><strong>Results: </strong>At baseline, 47.0%, 1.3% and 8.9% of participants reported a regular consumption (i.e. ≥4 days/week) of red meat, poultry and fish, respectively. After adjusting for adiposity and other potential confounders, each 50 g/day increase in red meat and fish intake was associated with 11% (HR 1.11 [95% CI 1.04, 1.20]) and 6% (HR 1.06 [95% CI 1.00, 1.13]) higher risk of incident diabetes, respectively. For both, the associations were more pronounced among men and women from urban areas, with an HR (95% CI) of 1.42 (1.15, 1.74) and 1.18 (1.03, 1.36), respectively, per 50 g/day red meat intake and 1.15 (1.02, 1.30) and 1.11 (1.01, 1.23), respectively, per 50 g/day fish intake. There was no significant association between diabetes and poultry intake, either overall (HR 0.96 [95% CI 0.83, 1.12] per 50 g/day intake) or in specific population subgroups.</br>
<br><strong>Conclusions/interpretation: </strong>In Chinese adults, both red meat and fish, but not poultry, intake were positively associated with diabetes risk, particularly among urban participants. Our findings add new evidence linking red meat and fish intake with cardiometabolic diseases.</br> |
| first_indexed | 2024-03-06T18:34:30Z |
| format | Journal article |
| id | oxford-uuid:0ac24193-053d-4561-9272-b3702f4565e8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:34:30Z |
| publishDate | 2020 |
| publisher | Springer |
| record_format | dspace |
| spelling | oxford-uuid:0ac24193-053d-4561-9272-b3702f4565e82022-03-26T09:25:48ZRed meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie BiobankJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:0ac24193-053d-4561-9272-b3702f4565e8EnglishSymplectic ElementsSpringer2020Du, HGuo, YBennett, DABragg, FBian, ZChadni, MYu, CChen, YTan, YMillwood, IYGan, WYang, LYao, PLuo, GLi, JQin, YLv, JLin, XKey, TChen, JClarke, RLi, LChen, ZChina Kadoorie Biobank collaborative group<br><strong>Aims/hypothesis: </strong>Previous evidence linking red meat consumption with diabetes risk mainly came from western countries, with little evidence from China, where patterns of meat consumption are different. Moreover, global evidence remains inconclusive about the associations of poultry and fish consumption with diabetes. Therefore we investigated the associations of red meat, poultry and fish intake with incidence of diabetes in a Chinese population.</br> <br><strong>Methods: </strong>The prospective China Kadoorie Biobank recruited ~512,000 adults (59% women, mean age 51 years) from ten rural and urban areas across China in 2004–2008. At the baseline survey, a validated interviewer-administered laptop-based questionnaire was used to collect information on the consumption frequency of major food groups including red meat, poultry, fish, fresh fruit and several others. During ~9 years of follow-up, 14,931 incidences of new-onset diabetes were recorded among 461,036 participants who had no prior diabetes, cardiovascular diseases or cancer at baseline. Cox regression analyses were performed to calculate adjusted HRs for incident diabetes associated with red meat, poultry and fish intake.</br> <br><strong>Results: </strong>At baseline, 47.0%, 1.3% and 8.9% of participants reported a regular consumption (i.e. ≥4 days/week) of red meat, poultry and fish, respectively. After adjusting for adiposity and other potential confounders, each 50 g/day increase in red meat and fish intake was associated with 11% (HR 1.11 [95% CI 1.04, 1.20]) and 6% (HR 1.06 [95% CI 1.00, 1.13]) higher risk of incident diabetes, respectively. For both, the associations were more pronounced among men and women from urban areas, with an HR (95% CI) of 1.42 (1.15, 1.74) and 1.18 (1.03, 1.36), respectively, per 50 g/day red meat intake and 1.15 (1.02, 1.30) and 1.11 (1.01, 1.23), respectively, per 50 g/day fish intake. There was no significant association between diabetes and poultry intake, either overall (HR 0.96 [95% CI 0.83, 1.12] per 50 g/day intake) or in specific population subgroups.</br> <br><strong>Conclusions/interpretation: </strong>In Chinese adults, both red meat and fish, but not poultry, intake were positively associated with diabetes risk, particularly among urban participants. Our findings add new evidence linking red meat and fish intake with cardiometabolic diseases.</br> |
| spellingShingle | Du, H Guo, Y Bennett, DA Bragg, F Bian, Z Chadni, M Yu, C Chen, Y Tan, Y Millwood, IY Gan, W Yang, L Yao, P Luo, G Li, J Qin, Y Lv, J Lin, X Key, T Chen, J Clarke, R Li, L Chen, Z China Kadoorie Biobank collaborative group Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank |
| title | Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank |
| title_full | Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank |
| title_fullStr | Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank |
| title_full_unstemmed | Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank |
| title_short | Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank |
| title_sort | red meat poultry and fish consumption and risk of diabetes a 9 year prospective cohort study of the china kadoorie biobank |
| work_keys_str_mv | AT duh redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT guoy redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT bennettda redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT braggf redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT bianz redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT chadnim redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT yuc redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT cheny redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT tany redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT millwoodiy redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT ganw redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT yangl redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT yaop redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT luog redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT lij redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT qiny redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT lvj redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT linx redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT keyt redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT chenj redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT clarker redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT lil redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT chenz redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank AT chinakadooriebiobankcollaborativegroup redmeatpoultryandfishconsumptionandriskofdiabetesa9yearprospectivecohortstudyofthechinakadooriebiobank |