Germline mutations of the LKB1 (STK11) gene in Peutz-Jeghers patients.

Germline mutations of the LKB1 (STK11) serine/threonine kinase gene (chromosome 19p13.3) cause Peutz-Jeghers syndrome, which is characterised by hamartomas of the gastrointestinal tract and typical pigmentation. Peutz-Jeghers syndrome carries an overall risk of cancer that may be up to 20 times that...

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Bibliographic Details
Main Authors:	Wang, Z, Churchman, M, Avizienyte, E, McKeown, C, Davies, S, Evans, D, Ferguson, A, Ellis, I, Xu, W, Yan, Z, Aaltonen, L, Tomlinson, I
Format:	Journal article
Language:	English
Published:	1999

Germline mutations of the LKB1 (STK11) gene in Peutz-Jeghers patients.

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