Identification of frequently recognized dimorphic T-cell epitopes in plasmodium falciparum merozoite surface protein-1 in West and East Africans: lack of correlation of immune recognition and allelic prevalence.

The merozoite surface protein-1 (MSP1) is the most studied malaria blood-stage vaccine candidate. Lymphokines such as interferon gamma (IFN-gamma) and interleukin 4 (IL-4) may mediate blood-stage specific protection. Here we identify Plasmodiumfalciparum MSP1 T-cell epitopes capable of rapid inducti...

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Bibliographic Details
Main Authors: Lee, E, Flanagan, K, Odhiambo, K, Reece, W, Potter, C, Bailey, R, Marsh, K, Pinder, M, Hill, A, Plebanski, M
Format: Journal article
Language:English
Published: 2001