TBX2 controls a proproliferative gene expression program in melanoma

Senescence shapes embryonic development, plays a key role in aging, and is a critical barrier to cancer initiation, yet how senescence is regulated remains incompletely understood. TBX2 is an antisenescence T-box family transcription repressor implicated in embryonic development and cancer. However,...

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Bibliographic Details
Main Authors: Lu, S, Louphrasitthiphol, P, Goradia, N, Lambert, J-P, Schmidt, J, Chauhan, J, Rughani, MG, Larue, L, Wilmanns, M, Goding, CR
Format: Journal article
Language:English
Published: Cold Spring Harbor Laboratory Press 2021