The effect of metformin and GANT61 combinations on the radiosensitivity of prostate cancer cells

The anti-diabetes drug metformin has been shown to have anti-neoplastic effects in several tumor models through its effects on energy metabolism and protein synthesis. Recent studies show that metformin also targets Hedgehog (Hh) signaling, a developmental pathway re-activated in several tumor types...

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Bibliographic Details
Main Authors: Gonnissen, A, Isebaert, S, McKee, C, Muschel, R, Haustermans, K
Format: Journal article
Language:English
Published: MDPI 2017