Analysis of the B cell receptor repertoire in six immune-mediated diseases

B cells are important in the pathogenesis of many, and perhaps all, immune-mediated diseases. Each B cell expresses a single B cell receptor (BCR)1, and the diverse range of BCRs expressed by the total B cell population of an individual is termed the ‘BCR repertoire’. Our understanding of the BCR re...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Bashford-Rogers, R, Bergamaschi, L, McKinney, E, Pombal, D, Mescia, F, Lee, J, Thomas, D, Flint, S, Kellam, P, Jayne, D, Lyons, P, Smith, K
Format: Journal article
Sprache:English
Veröffentlicht: Springer 2019