Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases.

The human MHC represents the strongest susceptibility locus for autoimmune diseases. However, the identification of the true predisposing gene(s) has been handicapped by the strong linkage disequilibrium across the region. Furthermore, most studies to date have been limited to the examination of a s...

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Bibliografiske detaljer
Main Authors: Rioux, J, Goyette, P, Vyse, T, Hammarström, L, Fernando, M, Green, T, De Jager, P, Foisy, S, Wang, J, de Bakker, P, Leslie, S, McVean, G, Padyukov, L, Alfredsson, L, Annese, V, Hafler, D, Pan-Hammarström, Q, Matell, R, Sawcer, S, Compston, A, Cree, B, Mirel, D, Daly, M, Behrens, T, Klareskog, L
Format: Journal article
Sprog:English
Udgivet: 2009