Genetic constraints and the adaptive evolution of rabies virus in nature
We used a molecular evolutionary approach to investigate the species adaptation of rabies virus in nature. A maximum likelihood analysis of selection pressures revealed that the nucleoprotein (N) and glycoprotein (G) genes of natural viral isolates were highly constrained, especially at nonsynonymou...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2002
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Subjects: |