Novel long-chain neurotoxins from Bungarus candidus distinguish the two binding sites in muscle-type nicotinic acetylcholine receptors

αδ-Bungarotoxins, a novel group of long-chain α-neurotoxins, manifest different affinity to two agonist/competitive antagonist binding sites of muscle-type nicotinic acetylcholine receptors, being more active at the interface of α-δ-subunits. Three isoforms (αδ-BgTx-1-3) were identified in Malayan K...

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Bibliographic Details
Main Authors: Utkin, YN, Kuch, U, Kasheverov, IE, Lebedev, DS, Cederlund, E, Molles, BE, Polyak, I, Ivanov, IA, Prokopev, NA, Ziganshin, RH, Jornvall, H, Alvelius, G, Chanhome, L, Warrell, D, Mebs, D, Bergman, T, Tsetlin, VI
Format: Journal article
Language:English
Published: Portland Press 2019