Exome resequencing identifies potential tumor-suppressor genes that predispose to colorectal cancer.

Exome resequencing identifies potential tumor-suppressor genes that predispose to colorectal cancer.

Show other versions (1)

Inherited factors account for around one third of all colorectal cancers (CRCs) and include rare high penetrance mutations in APC, MSH2, MSH6, and POLE. Here, we sought novel tumor-suppressor genes that predispose to CRC by exome resequencing 50 sporadic patients with advanced CRC (18 diagnosed ≤35...

Full description

Bibliographic Details
Main Authors: Smith, C, Naven, M, Harris, R, Colley, J, West, H, Li, N, Liu, Y, Adams, R, Maughan, T, Nichols, L, Kaplan, R, Wagner, M, McLeod, H, Cheadle, J
Format: Journal article
Language:English
Published: 2013

Similar Items