GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.

GATA3 has been identified as a master regulator of T helper cells, as well as being important for early thymic progenitors and T-cell commitment. However, Gata3 expression initiates already at the hematopoietic stem cell (HSC) level, implicating a potential role also in the regulation of HSCs. Herei...

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Bibliographic Details
Main Authors: Buza-Vidas, N, Duarte, S, Luc, S, Bouriez-Jones, T, Woll, P, Jacobsen, SE
Format: Journal article
Language:English
Published: 2011