GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.
GATA3 has been identified as a master regulator of T helper cells, as well as being important for early thymic progenitors and T-cell commitment. However, Gata3 expression initiates already at the hematopoietic stem cell (HSC) level, implicating a potential role also in the regulation of HSCs. Herei...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2011
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