HIV evolution: CTL escape mutation and reversion after transmission.

Within-patient HIV evolution reflects the strong selection pressure driving viral escape from cytotoxic T-lymphocyte (CTL) recognition. Whether this intrapatient accumulation of escape mutations translates into HIV evolution at the population level has not been evaluated. We studied over 300 patient...

Full description

Bibliographic Details
Main Authors:	Leslie, A, Pfafferott, K, Chetty, P, Draenert, R, Addo, M, Feeney, M, Tang, Y, Holmes, E, Allen, T, Prado, J, Altfeld, M, Brander, C, Dixon, C, Ramduth, D, Jeena, P, Thomas, SA, St John, A, Roach, T, Kupfer, B, Luzzi, G, Edwards, A, Taylor, G, Lyall, H, Tudor-Williams, G, Novelli, V
Format:	Journal article
Language:	English
Published:	2004

HIV evolution: CTL escape mutation and reversion after transmission.

Similar Items