HIV evolution: CTL escape mutation and reversion after transmission.

HIV evolution: CTL escape mutation and reversion after transmission.

Within-patient HIV evolution reflects the strong selection pressure driving viral escape from cytotoxic T-lymphocyte (CTL) recognition. Whether this intrapatient accumulation of escape mutations translates into HIV evolution at the population level has not been evaluated. We studied over 300 patient...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Leslie, A, Pfafferott, K, Chetty, P, Draenert, R, Addo, M, Feeney, M, Tang, Y, Holmes, E, Allen, T, Prado, J, Altfeld, M, Brander, C, Dixon, C, Ramduth, D, Jeena, P, Thomas, SA, St John, A, Roach, T, Kupfer, B, Luzzi, G, Edwards, A, Taylor, G, Lyall, H, Tudor-Williams, G, Novelli, V
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2004

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