Inhibition of BET bromodomain targets genetically diverse glioblastoma.
PURPOSE: Glioblastoma is refractory to conventional therapies. The bromodomain and extraterminal domain (BET) proteins are epigenetic readers that selectively bind to acetylated lysine residues on histone tails. These proteins recently emerged as important therapeutic targets in NUT midline carcinom...
| Main Authors: | , , , , , , , , , |
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| Format: | Conference item |
| Published: |
2013
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