Impact of intrapeptide epitope location on CD8 T cell recognition: implications for design of overlapping peptide panels.

BACKGROUND: Antigen-specific CD8 T cells following infection or immunization are typically assessed by measuring interferon-gamma production after stimulation with overlapping peptides spanning the region of interest. The effect of epitope location within such peptides is not known but may influenc...

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Bibliographic Details
Main Authors: Draenert, R, Brander, C, Yu, X, Altfeld, M, Verrill, C, Feeney, M, Walker, B, Goulder, P
Format: Journal article
Language:English
Published: 2004