The DNA translocase activity of FANCM protects stalled replication forks.

FANCM is the most highly conserved protein within the Fanconi anaemia (FA) tumour suppressor pathway. However, although FANCM contains a helicase domain with translocase activity, this is not required for its role in activating the FA pathway. Instead, we show here that FANCM translocaseactivity is...

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Bibliographic Details
Main Authors: Blackford, A, Schwab, R, Nieminuszczy, J, Deans, A, West, S, Niedzwiedz, W
Format: Journal article
Language:English
Published: 2012