The DNA translocase activity of FANCM protects stalled replication forks.
FANCM is the most highly conserved protein within the Fanconi anaemia (FA) tumour suppressor pathway. However, although FANCM contains a helicase domain with translocase activity, this is not required for its role in activating the FA pathway. Instead, we show here that FANCM translocaseactivity is...
Main Authors: | Blackford, A, Schwab, R, Nieminuszczy, J, Deans, A, West, S, Niedzwiedz, W |
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Format: | Journal article |
Language: | English |
Published: |
2012
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