Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia.

Patients with paraproteinemia have abnormalities in their T-cell subsets including inversion of the CD4:CD8 ratio and increased expression of activation markers. Recently, distortions in T-cell receptor (TCR) TCRAV and TCRBV gene segment expression have been reported, although the significance of th...

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Bibliographic Details
Main Authors: Moss, P, Gillespie, G, Frodsham, P, Bell, J, Reyburn, H
Format: Journal article
Language:English
Published: 1996