Conformational changes induced by salt in complexes of histones and superhelical nuclear DNA.
When HeLa cells are lysed in solutions containing a non-ionic detergent and 0.75 M-NaCl, structures are released that retain many of the morphological features of nuclei. These nucleoids contain all the nuclear DNA, RNA and the 'core' histones, but few other proteins characteristic of chro...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1981
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